A Translocation May Lead to Cancer if It

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Carcinogenesis also called oncogenesis or tumorigenesis is the formation of a cancer whereby normal cells are transformed into cancer cellsThe process is characterized by changes at the cellular genetic and epigenetic levels and abnormal cell divisionCell division is a physiological process that occurs in almost all tissues and under a variety of circumstances. Scientists have found mutations in approximately 20 different genes that they think may lead to pheochromocytoma and paraganglioma.


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Mutations in the genes RET VHL NF1 SDHA SDHB SDHC SDHD SDHAF2 MDH2 IDH1 PHD1 PHD2 HIF2A EPAS1 2 TMEM127 MAX HRAS MAML3 and CSDE1 may play a role in forming pheochromocytoma and paragangliomas.


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